Peptides

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Peptides are essential building blocks of proteins that keep the skin looking smooth, firm, and youthful. Applied topically, they can help to stimulate collagen and boost elasticity, visibly reducing the appearance of fine lines and wrinkles. Our innovative peptide skincare products feature expertly engineered peptide combinations for visible brightening, clarifying, and hydrating effects, delivering maximum results.
Medik8 Advanced Pro-Collagen+ Peptide Cream jar stands against a clean white background, with the open top revealing a rich white cream texture. Text on the jar highlights "Rejuvenating Anti-Wrinkle Moisturiser with GF MiniProtein & NAD+ Boost," while a geometric graphic in the corner reads "Growth Factor MP™ & NAD+ Longevity Booster."
Medik8 Advanced Pro-Collagen+ Peptide Cream jar displayed against a black background with abstract structural graphics. Text claims it helps increase collagen production by 45% for visibly firmer skin, reduced wrinkles, and increased elasticity.
Morning
Evening
Fine lines & wrinkles
Advanced Pro-Collagen+ Peptide Cream Rejuvenating Anti-Wrinkle Moisturiser With Growth Factor MiniProteinTM & NAD+ Longevity Booster
Full size (50ml) | $163
NEW
Medik8 Niacinamide Peptides serum bottle with a white pump top, resting on a white surface with a smear of white serum behind it.
A split image showing a close-up of skin texture labelled "Before" and "After 4 Weeks," highlighting improvements. Text on the left lists benefits: "Reduced blemishes," "Improved skin texture," "Reduced pore size," and "Soothed visible redness."
Morning
Evening
Enlarged pores & blemishes
Niacinamide Peptides 10% Niacinamide Serum with Peptides & NAG
Full size (30ml) | $105
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Medik8 Liquid Peptides Advanced MP serum bottle with awards on a white background
Liquid Peptides Advanced MP
Morning
Evening
Deep set lines & wrinkles
Liquid Peptides Advanced MP Wrinkle reduction serum with 30% multi-peptide complex - proven to deliver results in as little as 10 minutes.¹
$163
A purple glass dropper bottle of Bakuchiol Peptides serum, with its dropper removed. A swirl of the serum is shown, emphasising the product's texture.
A purple glass dropper bottle of Bakuchiol Peptides serum is shown with its dropper. To the left, text highlights the product as a "PLANT-BASED RETINOL ALTERNATIVE" with benefits including: smoothing fine lines & wrinkles, visibly evening skin tone & texture, calming, plumping & brightening skin's appearance, and being suitable for use while pregnant/nursing.
Morning
Evening
Fine lines & wrinkles
Bakuchiol Peptides™ Retinol Alternative Peptide-Infused Serum
Full Size (30ml) | $110
A clear glass dropper bottle of Liquid Peptides serum is presented, with its dropper removed and resting beside it and serum droplets, showing the texture
After 7 days: A before-and-after close-up of an eye and forehead area, showing visibly smoother skin in the circled section in the "After 7 Days" image compared to the "Before" side. Text highlights "Younger-looking skin in just 7 Days*". A bottle of Medik8 Liquid Peptides serum is shown in the corner alongside clear liquid bubble graphics.
Morning
Evening
Fine lines & wrinkles
Liquid Peptides™ 30% Complex Multi-Peptide Age-Defying Serum
Full Size (30ml) | $112
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Discover the No.1 Retinal Serum Worldwide

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An open frosted glass jar of Medik8 Total Moisture Daily Facial Cream with a peak of white cream on top, set against a clean white background. Badges in the top corners indicate it is a "Daisy Beauty Awards Vinnare 2025" (Winner) and "Dermatologist Recommended."
An image split between a white cream texture background and a smiling woman touching her radiant face. Text highlights key benefits with checkmarks: "Infuses moisture into the lowest layers of your skin," "Instantly plumps and softens your skin," and "Clinically proven to boost skin barrier function by +30% in 1 hour."
Morning
Evening
Dry & dehydrated skin
Total Moisture Daily Facial Cream™ AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Full Size (50ml) | $98
A tube of Eyelift Peptides stands upright, with a swatch of the product behind it.
A tube of Eyelift Peptides is displayed. Four bullet points with checkmarks list benefits: Visibly lifts eye contours & smooths fine lines, Reduces the look of dark circles & puffiness, Hydrates & comforts the delicate eye area, and Creates the ideal smoothing base for makeup.
Evening
Fine lines & wrinkles
Eyelift™ Peptides Age-Defying Firming Gel
Full Size | $100
Two small white bottles of Oxy-R Peptides serum are displayed. A black dropper tool lies nearby, and two drops of yellow serum are visible on the white surface
Two small white bottles of Oxy-R Peptides are displayed with drops of yellow serum. Text highlights PROFESSIONAL STRENGTH ACTION ON DARK SPOTS. Benefits listed are: Delivers brighter, more even skin in just 7 days, Fades visible dark spots in 1 month, Effective on all skin types & tones, and Hydrates & smooths the complexion.
Morning
Evening
Hyperpigmentation
Oxy-R Peptides™ High-Strength Oxyresveratrol Brightening Peptide Serum
Full Size (2 x 10ml) | $135
Medik8 Advanced Pro-Collagen+ Peptide Cream travel size jar on a white background
Medik8 Advanced Pro-Collagen+ Peptide Cream jar displayed against a black background with abstract structural graphics. Text claims it helps increase collagen production by 45% for visibly firmer skin, reduced wrinkles, and increased elasticity.
Morning
Evening
Advanced Pro-Collagen+ Peptide Cream (Travel size) Rejuvenating Anti-Wrinkle Moisturiser With Growth Factor MiniProteinTM & NAD+ Longevity Booster
$50
A travel-sized 12.5mL frosted jar of Medik8 Total Moisture Daily Facial Cream standing next to its white cardboard carton. The products are displayed on a textured grey surface against a clean white background. Text on both reads: "AM/PM Multi-Layered Moisturisation with H.E.O.™ & Prebiotic Peptides."
A travel-sized 12.5mL frosted jar of Medik8 Total Moisture Daily Facial Cream standing next to its white cardboard carton. The products are displayed on a textured grey surface against a clean white background. Text on both reads: "AM/PM Multi-Layered Moisturisation with H.E.O.™ & Prebiotic Peptides."
Morning
Evening
Total Moisture Daily Facial Cream™ (Travel size) AM/PM Multi-Layered Moisturisation with H.E.O.® & Prebiotic Peptides
Full Size (12.5ml) | $52
A small clear glass bottle (8mL) of Medik8 Liquid Peptides serum, with its dropper resting beside it. Text indicates it's ALSO AVAILABLE IN A HANDY TRAVEL SIZE.
Woman is applying Liquid Peptides serum with a dropper to their face. To the left, text states VISIBLE RESULTS IN JUST 7 DAYS* and lists benefits: Fine lines faded, Wrinkles minimised, Skin elasticity rejuvenated, Skin texture refined, and Hydration restored. A footnote indicates the claims are proven via an independent consumer study.
Morning
Evening
Liquid Peptides™ (Travel Size) 30% Complex Multi-Peptide Serum
$38

Frequently Asked Questions

Which types of peptides are most effective?

Peptides are a diverse group of active ingredients, each designed to target specific skin concerns. 

  • Signal peptides help stimulate collagen production, 
  • Carrier peptides support skin repair
  • Neurotransmitter peptides work to visibly soften the appearance of expression lines.

The most advanced formulations combine multiple peptide types to deliver comprehensive anti-ageing benefits and support overall skin renewal.

Liquid Peptides Advanced is Medik8’s next-generation peptide serum, formulated with a 30% multi-peptide blend and powered by Dual MiniProteins™ to visibly target both early and deep-set wrinkles.

Are peptides suitable for sensitive skin?
Yes, peptides are generally very well tolerated, even by sensitive skin. Their gentle nature makes them ideal for supporting skin that’s prone to irritation, as they help to calm, hydrate and reinforce the skin barrier. As with any new product, we recommend patch testing first, especially if your skin is reactive or compromised.

Can you use peptides when pregnant?

Peptides are generally considered safe to use during pregnancy. Unlike ingredients such as retinoids, peptides do not pose known risks and can continue to support the skin through hydration and repair. However, if you’re unsure, it’s always best to check with a healthcare provider.

Can you use peptides with retinol?

Peptides and retinol aren’t rivals, they’re complementary. While retinol encourages skin renewal and boosts collagen production, it can sometimes cause dryness or irritation, particularly for sensitive skin. Peptides, on the other hand, help to firm, smooth and support the skin barrier more gently.

Using both in a balanced routine can deliver powerful results. Peptides can help buffer the effects of retinol, making the combination ideal for visibly improving signs of ageing without compromising comfort. 

Medik8’s Crystal Retinal pairs well with Liquid Peptides in a balanced evening routine.

Which peptides are best for anti-ageing?

Different peptides target different signs of ageing, which is why combining them often delivers the most visible results. Signal peptides help stimulate collagen production, while neurotransmitter peptides visibly smooth expression lines. Carrier peptides support skin regeneration, and enzyme-inhibitor peptides help slow the breakdown of collagen and elastin.

Medik8’s Liquid Peptides Advanced features a 30% blend of 10 carefully selected peptides, including our pioneering Dual MiniProteins™. This next-generation formula is clinically proven to visibly reduce both expression lines and deeper wrinkles, offering comprehensive, targeted support for firmer, smoother-looking skin[1].

[1]To verify visit: https://www.medik8.com/pages/circana-group-claim-letters-liquid-peptides-advanced-mp

Do I use Niacinamide Peptides in the morning or in the evening?
Both. Niacinamide Peptides can be used after cleansing day or night.

Can I use Exo-PDRN Prismatic+ with Liquid Peptides Advanced MP?

Absolutely. Exo-PDRN Prismatic+ and Liquid Peptides Advanced MP make an ideal age-defying duo. Use Liquid Peptides Advanced MP to target expression lines and build visible wrinkle reduction and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.

When and how should I apply Bakuchiol Peptides?
Bakuchiol Peptides can be applied both morning and night. After cleansing in the morning and evening, massage 6 drops across the face, neck and décolletage. Follow with a sunscreen (AM) and moisturiser (PM).

Do I use Niacinamide Peptides in the morning or in the evening?
Both. Niacinamide Peptides can be used after cleansing day or night.

Can I use Exo-PDRN Prismatic+ with Liquid Peptides Advanced MP?

Absolutely. Exo-PDRN Prismatic+ and Liquid Peptides Advanced MP make an ideal age-defying duo. Use Liquid Peptides Advanced MP to target expression lines and build visible wrinkle reduction and Exo-PDRN Prismatic+ to support long-term skin rejuvenation, resilience and recovery.

When and how should I apply Bakuchiol Peptides?
Bakuchiol Peptides can be applied both morning and night. After cleansing in the morning and evening, massage 6 drops across the face, neck and décolletage. Follow with a sunscreen (AM) and moisturiser (PM).

Shop by Peptides

Skin-signalling science

Peptides are short chains of essential amino acids that act as messengers, signalling the skin to boost firmness, smoothness, and visible elasticity. By targeting expression lines and loss of tone, they offer a refined approach to age-defying skincare.

Flexible, routine-friendly performance

Suitable for both morning and evening use, peptide serums layer easily after cleansing and before moisturiser. For restorative results, peptides and retinal are a dream duo. Our Liquid Peptides Advanced MP makes a perfect pairing with Crystal Retinal to support a more youthful-looking complexion. Prefer a clarifying finish? Niacinamide Peptides combines 10% niacinamide with peptides to refine the look of pores and smooth congested texture, leaving oily and blemish-prone skin with a fresh, glass-like glow.

Developed with clinical integrity

Our peptide range has been developed using advanced, precision technologies tailored to each formula. From our proprietary MiniProteins™ for enhanced performance, to multi-peptide complexes featuring Matrixyl and carnosine, every product is backed by clinical insight to help visibly improve your skin and its individual needs.